Fig. 4

Osteoblastic activity of hOBs and SaOS-2 cells grown on 2D or on 3D-printed collagen, or on PEGDA scaffolds, assessed by ALP and LDH activity measurement. ALP activity normalized by LDH activity in hOBs (A) and SaOS-2 cells (B) grown in 2D in non-coated wells or in collagen-coated wells, and in 3D on PEGDA and collagen scaffolds. hOBs, human osteoblasts; ALP, alkaline phosphatase; LDH, lactate dehydrogenase; *p < 0.05, **p < 0.005